GADD45GIP1 anticorps (Middle Region)
-
- Antigène Voir toutes GADD45GIP1 Anticorps
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
-
Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Chien, Cobaye, Lapin, Cheval, Porc, Saccharomyces cerevisiae, Boeuf (Vache)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp GADD45GIP1 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- SLRVKQLAEE QKRREREQHI AECMAKMPQM IVNWQQQQRE NWEKAQADKE
- Homologie
- Cow: 90%, Dog: 90%, Guinea Pig: 85%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 92%, Rabbit: 85%, Rat: 92%, Yeast: 91%
- Attributs du produit
- This is a rabbit polyclonal antibody against GADD45GIP1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GADD45GIP1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 222 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
- Autre désignation
- GADD45GIP1 (GADD45GIP1 Produits)
- Synonymes
- anticorps si:dkey-194e13.6, anticorps CKBBP2, anticorps CRIF1, anticorps PLINP, anticorps PLINP-1, anticorps PRG6, anticorps Plinp1, anticorps 2310040G17Rik, anticorps AI425883, anticorps Crif1, anticorps growth arrest and DNA-damage-inducible, gamma interacting protein 1, anticorps GADD45G interacting protein 1, anticorps gadd45gip1, anticorps GADD45GIP1, anticorps Gadd45gip1
- Sujet
-
GADD45GIP1 acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. GADD45GIP1 acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. GADD45GIP1 may be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Alias Symbols: CKBBP2, CRIF1, MGC4667, MGC4758, PLINP-1, PRG6, Plinp1
Protein Interaction Partner: FBXW11, UBC, LIN28A, EXOSC4, UPF2, TMEM177, MRPL11, MRPL14, TSR1, PTRH2, EIF3C, TAP1, MRPL12, APP, COPS5, HNRNPA1, NFE2L2, ICT1, AR, IKBKG, GADD45G, GADD45B, NR4A1, GADD45A, CSNK2B,
Protein Size: 222 - Poids moléculaire
- 24 kDa
- ID gène
- 90480
- NCBI Accession
- NM_052850, NP_443082
- UniProt
- Q8TAE8
-