HSP90AA1 anticorps (AA 380-732)

N° du produit ABIN7114903

Cet anticorps Souris Monoclonal détecte spécifiquement HSP90AA1 dans WB, IHC, ELISA et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour HSP90AA1 anticorps (AA 380-732) (ABIN7114903)

Antigène: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSP90AA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Clone: 4G10

Détail du produit anti-HSP90AA1 anticorps

Épitope: AA 380-732

Fonction: HSP90AA1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 380-732aa

Immunogen: heat shock protein 90kDa alpha(cytosolic), class A member 1

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000-1:8000, IHC: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur HSP90AA1

Antigène: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Autre désignation: HSP90AA1

Sujet:

Synonyms: Heat shock protein HSP 90-alpha|Heat shock 86 kDa (HSP 86, HSP86)|Lipopolysaccharide-associated protein 2 (LAP-2, LPS-associated protein 2)|Renal carcinoma antigen NY-REN-38|HSP90AA1|HSP90A|HSPC1|HSPCA

Background: HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins, many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.

Poids moléculaire: 90 kDa

ID gène: 3320

UniProt: P07900

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals