HSD3B7 anticorps

N° du produit ABIN7115138

L’anticorps Lapin Polyclonal anti-HSD3B7 a été validé pour ELISA, WB et IHC. Il convient pour détecter HSD3B7 dans des échantillons de Humain et Souris.

Aperçu rapide pour HSD3B7 anticorps (ABIN7115138)

Antigène: HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD3B7 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HSD3B7 anticorps

Fonction: HSD3B7 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 7

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur HSD3B7

Antigène: HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))

Autre désignation: HSD3B7

Sujet:

Synonyms: 3 beta-hydroxysteroid dehydrogenase type 7|3 beta-hydroxysteroid dehydrogenase type VII (3-beta-HSD VII)|3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase (C(27) 3-beta-HSD)|Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase|HSD3B7

Background: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis(PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.

Poids moléculaire: 36 kDa

ID gène: 80270

UniProt: Q9H2F3