HSD3B7 anticorps (AA 131-197) (HRP)

N° du produit ABIN7142283

Détail du produit anti-HSD3B7 anticorps (HRP)

Antigène: HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))

Épitope: AA 131-197

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD3B7 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human 3 beta-hydroxysteroid dehydrogenase type 7 protein (131-197AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HSD3B7

Antigène: HSD3B7 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 7 (HSD3B7))

Autre désignation: HSD3B7 (HSD3B7 Produits)

Synonymes: anticorps CBAS1, anticorps PFIC4, anticorps SDR11E3, anticorps AI195443, anticorps BB098564, anticorps Cca2, anticorps hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7, anticorps HSD3B7, anticorps Hsd3b7

Sujet:

Background: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.

Aliases: HSD3B73 beta-hydroxysteroid dehydrogenase type 7 antibody, 3 beta-hydroxysteroid dehydrogenase type VII antibody, 3-beta-HSD VII antibody, 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase antibody, C(27) 3-beta-HSD antibody, EC 1.1.1.- antibody, Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase antibody, EC 1.1.1.181 antibody

UniProt: Q9H2F3