HSD17B6 anticorps
Aperçu rapide pour HSD17B6 anticorps (ABIN7115154)
Antigène
Voir toutes HSD17B6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- HSD17B6 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- hydroxysteroid(17-beta) dehydrogenase 6 homolog(Mouse)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))
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Autre désignation
- HSD17B6
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Sujet
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Synonyms: 17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6, 17-beta-HSD6)|3-alpha->beta-hydroxysteroid epimerase (3-alpha->beta-HSE)|Oxidative 3-alpha hydroxysteroid dehydrogenase|Short chain dehydrogenase/reductase family 9C member 6|HSD17B6|RODH|SDR9C6
Background: NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity(in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids(in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone(in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone(in vitro). Has retinol dehydrogenase activity towards all-trans-retinol(in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
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Poids moléculaire
- 33-35 kDa
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ID gène
- 8630
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UniProt
- O14756
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Pathways
- Steroid Hormone Biosynthesis
Antigène
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