ING4 anticorps

N° du produit ABIN7115237

L’anticorps Lapin Polyclonal anti-ING4 a été validé pour WB, ELISA, IHC, IP et IF. Il convient pour détecter ING4 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ING4 anticorps (ABIN7115237)

Antigène: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ING4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-ING4 anticorps

Fonction: ING4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: inhibitor of growth family, member 4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ING4

Antigène: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Autre désignation: ING4

Sujet:

Synonyms: Inhibitor of growth protein 4|p29ING4|ING4

Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's(HIF) activity by interacting with HIF prolyl hydroxylase 2(EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11(By similarity).

Poids moléculaire: 29 kDa

ID gène: 51147

UniProt: Q9UNL4