IWS1 anticorps

N° du produit ABIN7115537

L’anticorps Lapin Polyclonal anti-IWS1 a été validé pour WB, ELISA et IP. Il convient pour détecter IWS1 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour IWS1 anticorps (ABIN7115537)

Antigène: IWS1 (IWS1 Homolog (IWS1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IWS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-IWS1 anticorps

Fonction: IWS1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: IWS1 homolog

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur IWS1

Antigène: IWS1 (IWS1 Homolog (IWS1))

Autre désignation: IWS1

Sujet:

Synonyms: Protein IWS1 homolog|IWS1-like protein|IWS1|IWS1L

Background: Transcription factor which plays a key role in defining the composition of the RNA polymerase II(RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain(CTD) of the RNAPII subunit RPB1(POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors(ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes(such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Poids moléculaire: 116-120 kDa

ID gène: 55677

UniProt: Q96ST2