Cytokeratin 18 anticorps (AA 127-430)

N° du produit ABIN7115628

Cet anticorps anti-Cytokeratin 18 est un anticorps Souris Monoclonal détectant Cytokeratin 18 dans WB, IHC, IF, FACS et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Cytokeratin 18 anticorps (AA 127-430) (ABIN7115628)

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 18 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA

Clone: 6E3

Détail du produit anti-Cytokeratin 18 anticorps

Épitope: AA 127-430

Fonction: KRT18 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 127-430aa

Immunogen: keratin 18

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:5000-1:30000, IHC: 1:500-1:1000, IF: 1:100-1:300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Cytokeratin 18

Antigène: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Autre désignation: KRT18

Sujet:

Synonyms: Keratin, type I cytoskeletal 18|Cell proliferation-inducing gene 46 protein|Cytokeratin-18 (CK-18)|Keratin-18 (K18)|KRT18|CYK18

Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.

Poids moléculaire: 48 kDa

ID gène: 3875

UniProt: P05783

Pathways: Apoptose, Caspase Cascade in Apoptosis