LGR6 anticorps
Aperçu rapide pour LGR6 anticorps (ABIN7115835)
Antigène
Voir toutes LGR6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- LGR6 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- leucine-rich repeat-containing G protein-coupled receptor 6
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Isotype
- IgG
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Indications d'application
- WB: 1:200-1:1000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))
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Autre désignation
- LGR6
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Sujet
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Synonyms: Leucine-rich repeat-containing G-protein coupled receptor 6|LGR6
Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
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Poids moléculaire
- 104 kDa
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ID gène
- 59352
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UniProt
- Q9HBX8
Antigène
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