LNX1 anticorps
Aperçu rapide pour LNX1 anticorps (ABIN7115860)
Antigène
Voir toutes LNX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- LNX1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- ligand of numb-protein X 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
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Autre désignation
- LNX1
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Sujet
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Synonyms: E3 ubiquitin-protein ligase LNX|Ligand of Numb-protein X 1|Numb-binding protein 1|PDZ domain-containing RING finger protein 2|RING-type E3 ubiquitin transferase LNX|LNX1|LNX|PDZRN2
Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65(By similarity). Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
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Poids moléculaire
- 70 kDa
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ID gène
- 84708
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UniProt
- Q8TBB1
Antigène
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