KDM5C anticorps

N° du produit ABIN7115965

Cet anticorps Lapin Polyclonal détecte spécifiquement KDM5C dans ELISA et WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour KDM5C anticorps (ABIN7115965)

Antigène: KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM5C est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-KDM5C anticorps

Fonction: KDM5C antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: lysine(K)-specific demethylase 5C

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur KDM5C

Antigène: KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))

Autre désignation: KDM5C

Sujet:

Synonyms: Lysine-specific demethylase 5C|Histone demethylase JARID1C|Jumonji/ARID domain-containing protein 1C|Protein SmcX|Protein Xe169|[histone H3]-trimethyl-L-lysine(4) demethylase 5C|KDM5C|DXS1272E|JARID1C|SMCX|XE169

Background: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2(By similarity).

Poids moléculaire: 171-180 kDa

ID gène: 8242

UniProt: P41229

Pathways: L'effet Warburg