MSL1 anticorps (AA 473-614)

N° du produit ABIN7116032

L’anticorps Lapin Polyclonal anti-MSL1 a été validé pour WB et ELISA. Il convient pour détecter MSL1 dans des échantillons de Humain.

Aperçu rapide pour MSL1 anticorps (AA 473-614) (ABIN7116032)

Antigène: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MSL1 anticorps

Épitope: AA 473-614

Fonction: MSL1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 473-614aa

Immunogen: male-specific lethal 1 homolog(Drosophila)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MSL1

Antigène: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Autre désignation: MSL1

Sujet:

Synonyms: Male-specific lethal 1 homolog (MSL-1)|Male-specific lethal 1-like 1 (MSL1-like 1)|Male-specific lethal-1 homolog 1|MSL1|MSL1L1

Background: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.

Poids moléculaire: 67 kDa

ID gène: 339287

UniProt: Q68DK7