MAGED1 anticorps

N° du produit ABIN7116167

L’anticorps Lapin Polyclonal anti-MAGED1 a été validé pour WB, IHC, ELISA et IF. Il convient pour détecter MAGED1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MAGED1 anticorps (ABIN7116167)

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAGED1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-MAGED1 anticorps

Fonction: MAGED1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: melanoma antigen family D, 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MAGED1

Antigène: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Autre désignation: MAGED1

Sujet:

Synonyms: Melanoma-associated antigen D1|MAGE tumor antigen CCF|MAGE-D1 antigen|Neurotrophin receptor-interacting MAGE homolog|MAGED1|NRAGE

Background: Involved in the apoptotic response after nerve growth factor(NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.

Poids moléculaire: 100 kDa

ID gène: 9500

UniProt: Q9Y5V3

Pathways: Neurotrophin Signaling Pathway