MME anticorps
Aperçu rapide pour MME anticorps (ABIN7116192)
Antigène
Voir toutes MME AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- MME antibody
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Purification
- Protein A+G purification
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- membrane metallo-endopeptidase
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Isotype
- IgG2a
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Indications d'application
- WB: 1:500-1:5000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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Autre désignation
- MME
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Sujet
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Synonyms: Neprilysin|Atriopeptidase|Common acute lymphocytic leukemia antigen (CALLA)|Enkephalinase|Neutral endopeptidase 24.11 (NEP, Neutral endopeptidase)|Skin fibroblast elastase (SFE)|MME|EPN
Background: MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).This antibody is specific to MME.
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Poids moléculaire
- 90-110 kDa
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ID gène
- 4311
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UniProt
- P08473
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Pathways
- Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
Antigène
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