MGEA5 anticorps (AA 430-630)

N° du produit ABIN7116206

L’anticorps Lapin Polyclonal anti-MGEA5 a été validé pour WB, IHC, IP, ELISA et IF. Il convient pour détecter MGEA5 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MGEA5 anticorps (AA 430-630) (ABIN7116206)

Antigène: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGEA5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Détail du produit anti-MGEA5 anticorps

Épitope: AA 430-630

Fonction: OGA antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 430-630aa

Immunogen: meningioma expressed antigen 5(hyaluronidase)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MGEA5

Antigène: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Autre désignation: OGA

Sujet:

Synonyms: Protein O-GlcNAcase (OGA)|Beta-N-acetylglucosaminidase|Beta-N-acetylhexosaminidase|Beta-hexosaminidase|Meningioma-expressed antigen 5|N-acetyl-beta-D-glucosaminidase|N-acetyl-beta-glucosaminidase|Nuclear cytoplasmic O-GlcNAcase and acetyltransferase (NCOAT)|OGA|HEXC|KIAA0679|MEA5|MGEA5

Background: Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc(in vitro)(PubMed:11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity(PubMed:24088714). Isoform 3: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc(in vitro), but has about six times lower specific activity than isoform 1.

Poids moléculaire: 130 kDa

ID gène: 10724

UniProt: O60502

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process