MBD2 anticorps
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- Antigène Voir toutes MBD2 Anticorps
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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Reactivité
- Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MBD2 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- methyl-CpG binding domain protein 2
- Isotype
- IgG
- Top Product
- Discover our top product MBD2 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
- Autre désignation
- MBD2 (MBD2 Produits)
- Synonymes
- anticorps MBD2, anticorps DMTase, anticorps NY-CO-41, anticorps MBD2a, anticorps wu:fa97f06, anticorps zgc:111862, anticorps methyl-CpG binding domain protein 2, anticorps methyl-CpG binding domain protein 2 S homeolog, anticorps MBD2, anticorps Mbd2, anticorps mbd2, anticorps mbd2.S
- Sujet
- Synonyms: Background:Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
- Poids moléculaire
- 43-45 kDa
- ID gène
- 8932
- UniProt
- Q9UBB5
- Pathways
- Chromatin Binding
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