MICAL1 anticorps
Aperçu rapide pour MICAL1 anticorps (ABIN7116285)
Antigène
Voir toutes MICAL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- MICAL1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- microtubule associated monoxygenase, calponin and LIM domain containing 1
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Isotype
- IgG
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Indications d'application
- WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
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Autre désignation
- MICAL1
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Sujet
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Synonyms: [F-actin]-monooxygenase MICAL1|Molecule interacting with CasL protein 1 (MICAL-1)|NEDD9-interacting protein with calponin homology and LIM domains|MICAL1|MICAL|NICAL
Background: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization(Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L, acts by antagonizing STK38 and STK38L activation by MST1/STK4.
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Poids moléculaire
- 120 kDa
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ID gène
- 64780
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UniProt
- Q8TDZ2
Antigène
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