MICAL1 anticorps (AA 806-1067) (FITC)
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- Antigène Voir toutes MICAL1 Anticorps
- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
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Épitope
- AA 806-1067
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MICAL1 est conjugé à/à la FITC
- Application
- Veuillez nous consulter SVP
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human [F-actin]-methionine sulfoxide oxidase MICAL1 protein (806-1067AA)
- Isotype
- IgG
- Top Product
- Discover our top product MICAL1 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- MICAL1 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 1 (MICAL1))
- Autre désignation
- MICAL1 (MICAL1 Produits)
- Synonymes
- anticorps MICAL, anticorps MICAL-1, anticorps NICAL, anticorps Nical, anticorps zgc:171928, anticorps microtubule associated monooxygenase, calponin and LIM domain containing 1, anticorps MICAL1, anticorps Mical1, anticorps mical1
- Sujet
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Background: Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin. Acts by modifying actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization (Probable). Acts as a cytoskeletal regulator that connects NEDD9 to intermediate filaments. Also acts as a negative regulator of apoptosis via its interaction with STK38 and STK38L, acts by antagonizing STK38 and STK38L activation by MST1/STK4. Involved in regulation of lamina-specific connectivity in the nervous system such as the development of lamina-restricted hippocampal connections. Through redox regulation of the actin cytoskeleton controls the intracellular distribution of sectrory vesicles containing L1/neurofascin/NgCAM family proteins in neurons, thereby regulating their cell surface levels (By similarity). May act as Rab effector protein and play a role in vesicle trafficking.
Aliases: CasL interacting molecule antibody, DKFZp434B1517 antibody, FLJ11937 antibody, FLJ21739 antibody, MICA1_HUMAN antibody, MICAL 1 antibody, MICAL antibody, MICAL1 antibody, microtubule associated monoxygenase, calponin and LIM domain containing 1 antibody, Molecule interacting with CasL protein 1 antibody, NEDD9 interacting protein with calponin homology and LIM domains antibody, NEDD9-interacting protein with calponin homology and LIM domains antibody, NICAL antibody, OTTHUMP00000016969 antibody
- UniProt
- Q8TDZ2
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