NFIL3 anticorps

N° du produit ABIN7116970

Cet anticorps Lapin Polyclonal détecte spécifiquement NFIL3 dans WB, ELISA et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour NFIL3 anticorps (ABIN7116970)

Antigène: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFIL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-NFIL3 anticorps

Fonction: NFIL3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: nuclear factor, interleukin 3 regulated

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur NFIL3

Antigène: NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

Autre désignation: NFIL3

Sujet:

Synonyms: Nuclear factor interleukin-3-regulated protein|E4 promoter-binding protein 4|Interleukin-3 promoter transcriptional activator|Interleukin-3-binding protein 1|Transcriptional activator NF-IL3A|NFIL3|E4BP4|IL3BP1

Background: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor(ATF) sites. Represses promoter activity in osteoblasts(By similarity). Represses transcriptional activity of PER1(By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter(By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors(DBP, HLF and TEF)(By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock(By similarity). Protects pro-B cells from programmed cell death(By similarity).

Poids moléculaire: 55-60 kDa

ID gène: 4783

UniProt: Q16649