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NUMBL anticorps

NUMBL Reactivité: Humain WB, ELISA, IHC Hôte: Souris Monoclonal 8E0 unconjugated
N° du produit ABIN7117092
  • Antigène Voir toutes NUMBL Anticorps
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    Reactivité
    • 46
    • 9
    • 9
    • 1
    Humain
    Hôte
    • 45
    • 1
    Souris
    Clonalité
    • 46
    Monoclonal
    Conjugué
    • 11
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NUMBL est non-conjugé
    Application
    • 31
    • 21
    • 15
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Protein A+G purification
    Pureté
    ≥95 % as determined by SDS-PAGE
    Immunogène
    numb homolog(Drosophila)-like
    Clone
    8E0
    Isotype
    IgG2a
    Top Product
    Discover our top product NUMBL Anticorps primaire
  • Indications d'application
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Date de péremption
    12 months
  • Antigène
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    Autre désignation
    NUMBL (NUMBL Produits)
    Synonymes
    anticorps nbl, anticorps numb, anticorps cag3a, anticorps ctg3a, anticorps numbr, anticorps numb-r, anticorps tnrc23, anticorps numblike, anticorps CAG3A, anticorps CTG3a, anticorps NBL, anticorps NUMB-R, anticorps NUMBLIKE, anticorps NUMBR, anticorps TNRC23, anticorps NUMB like, endocytic adaptor protein, anticorps numb homolog-like L homeolog, anticorps NUMB-like, endocytic adaptor protein, anticorps numb-like, anticorps NUMBL, anticorps numbl.L, anticorps Numbl
    Sujet
    Synonyms: Background:Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells(RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone(SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
    Poids moléculaire
    70 kDa
    ID gène
    9253
    UniProt
    Q9Y6R0
    Pathways
    Cell-Cell Junction Organization
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