PDE12 anticorps

N° du produit ABIN7117422

Cet anticorps anti-PDE12 est un anticorps Lapin Polyclonal détectant PDE12 dans WB, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PDE12 anticorps (ABIN7117422)

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-PDE12 anticorps

Fonction: PDE12 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: phosphodiesterase 12

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PDE12

Antigène: PDE12 (Phosphodiesterase 12 (PDE12))

Autre désignation: PDE12

Sujet:

Synonyms: 2',5'-phosphodiesterase 12 (2'-PDE, 2-PDE)|Mitochondrial deadenylase|PDE12

Background: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons(IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.

Poids moléculaire: 65 kDa

ID gène: 201626

UniProt: Q6L8Q7