PGK1 anticorps

N° du produit ABIN7117449

Cet anticorps anti-PGK1 est un anticorps Lapin Polyclonal détectant PGK1 dans WB, ELISA, IHC et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PGK1 anticorps (ABIN7117449)

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PGK1 anticorps

Fonction: PGK1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: phosphoglycerate kinase 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PGK1

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Autre désignation: PGK1

Sujet:

Synonyms: Phosphoglycerate kinase 1|Cell migration-inducing gene 10 protein|Primer recognition protein 2 (PRP 2)|PGK1|PGKA

Background: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1, 3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.

Poids moléculaire: 47 kDa

ID gène: 5230

UniProt: P00558

Pathways: Cellular Glucan Metabolic Process