PHKG2 anticorps
Aperçu rapide pour PHKG2 anticorps (ABIN7117512)
Antigène
Voir toutes PHKG2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PHKG2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- phosphorylase kinase, gamma 2 (testis)
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))
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Autre désignation
- PHKG2
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Sujet
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Synonyms: Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT, PHK-gamma-T)|PSK-C3|Phosphorylase kinase subunit gamma-2|PHKG2
Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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Poids moléculaire
- 46 kDa
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ID gène
- 5261
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UniProt
- P15735
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Pathways
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
Antigène
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