POLI anticorps
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- Antigène Voir toutes POLI Anticorps
- POLI (Polymerase (DNA Directed) iota (POLI))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp POLI est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- polymerase(DNA directed) iota
- Isotype
- IgG
- Top Product
- Discover our top product POLI Anticorps primaire
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anti-Polymerase (DNA Directed) iota (POLI) (AA 616-715) antibody
POLI Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 8G9 unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (N-Term) antibodyPOLI Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 458-711) antibodyPOLI Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (N-Term) antibodyPOLI Reactivité: Humain WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 50-350) antibodyPOLI Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 458-740) antibodyPOLI Reactivité: Humain WB, IHC, IHC (p) Hôte: Souris Monoclonal 1B9 unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (C-Term) antibodyPOLI Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 51-150) antibodyPOLI Reactivité: Rat ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (AA 143-192) antibodyPOLI Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Roussette (Chauve-souris), Singe, Porc WB Hôte: Lapin Polyclonal unconjugated
anti-Polymerase (DNA Directed) iota (POLI) (N-Term) antibodyPOLI Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin, Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- POLI (Polymerase (DNA Directed) iota (POLI))
- Autre désignation
- POLI (POLI Produits)
- Synonymes
- anticorps poli, anticorps wu:fc27h11, anticorps zgc:110185, anticorps GB12093, anticorps NV16187, anticorps RAD30B, anticorps RAD3OB, anticorps Rad30b, anticorps DNA polymerase iota, anticorps polymerase (DNA directed) iota, anticorps polymerase (DNA directed), iota, anticorps POLI, anticorps poli, anticorps LOC551219, anticorps AFUA_4G11140, anticorps LOC5568276, anticorps Pol-iota, anticorps Poli
- Sujet
- Synonyms:DNA polymerase iota, Eta2, POLI, polymerase (DNA directed) iota, RAD30 homolog B, RAD30B, RAD3OB Background:Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity.
- Poids moléculaire
- 87 kDa
- ID gène
- 11201
- UniProt
- Q9UNA4
- Pathways
- Réparation de l'ADN
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