PA2G4 anticorps

N° du produit ABIN7117814

L’anticorps Souris Monoclonal anti-PA2G4 a été validé pour WB, ELISA, IHC et IF. Il convient pour détecter PA2G4 dans des échantillons de Humain.

Aperçu rapide pour PA2G4 anticorps (ABIN7117814)

Antigène: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PA2G4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 5C6

Détail du produit anti-PA2G4 anticorps

Fonction: PA2G4 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: proliferation-associated 2G4, 38kDa

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:50-1:500, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PA2G4

Antigène: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Autre désignation: PA2G4

Sujet:

Synonyms: Proliferation-associated protein 2G4|Cell cycle protein p38-2G4 homolog (hG4-1)|ErbB3-binding protein 1|PA2G4|EBP1

Background: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor(AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin(HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase(HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs(internal ribosomal entry site)(By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation(By similarity).

Poids moléculaire: 48 kDa

ID gène: 5036

UniProt: Q9UQ80

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades