PSMC6 anticorps

N° du produit ABIN7117883

L’anticorps anti-PSMC6 Polyclonal Lapin est utilisé pour la détection de PSMC6 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour PSMC6 anticorps (ABIN7117883)

Antigène: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PSMC6 anticorps

Fonction: PSMC6 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: proteasome (prosome, macropain) 26S subunit, ATPase, 6

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PSMC6

Antigène: PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))

Autre désignation: PSMC6

Sujet:

Synonyms: 26S proteasome regulatory subunit 10B|26S proteasome AAA-ATPase subunit RPT4|Proteasome 26S subunit ATPase 6|Proteasome subunit p42|PSMC6|SUG2

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Poids moléculaire: 45 kDa

ID gène: 5706

UniProt: P62333

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway