RACGAP1 anticorps (AA 400-632)

N° du produit ABIN7118247

Cet anticorps anti-RACGAP1 est un anticorps Souris Monoclonal détectant RACGAP1 dans WB, IHC, ELISA et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RACGAP1 anticorps (AA 400-632) (ABIN7118247)

Antigène: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RACGAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 1B5

Détail du produit anti-RACGAP1 anticorps

Épitope: AA 400-632

Fonction: RACGAP1 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 400-632aa

Immunogen: Rac GTPase activating protein 1

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:20-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RACGAP1

Antigène: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Autre désignation: RACGAP1

Sujet:

Synonyms: Rac GTPase-activating protein 1|Male germ cell RacGap (MgcRacGAP)|Protein CYK4 homolog (CYK4, HsCYK-4)|RACGAP1|KIAA1478|MGCRACGAP

Background: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP(GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Poids moléculaire: 71 kDa

ID gène: 29127

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor