RAD17 anticorps
Aperçu rapide pour RAD17 anticorps (ABIN7118250)
Antigène
Voir toutes RAD17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RAD17 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- RAD17 homolog(S. pombe)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- RAD17
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Autre désignation
- RAD17
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Sujet
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Synonyms: Cell cycle checkpoint protein RAD17 (hRad17)|RF-C/activator 1 homolog|RAD17|R24L
Background: Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
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Poids moléculaire
- 71 kDa
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ID gène
- 5884
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UniProt
- O75943
Antigène
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