RAD51D anticorps

N° du produit ABIN7118256

Cet anticorps anti-RAD51D est un anticorps Lapin Polyclonal détectant RAD51D dans WB, ELISA et IHC. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour RAD51D anticorps (ABIN7118256)

Antigène: RAD51D (RAD51 Homolog D (RAD51D))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51D est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RAD51D anticorps

Fonction: RAD51D antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: RAD51-like 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RAD51D

Antigène: RAD51D (RAD51 Homolog D (RAD51D))

Autre désignation: RAD51D

Sujet:

Synonyms: DNA repair protein RAD51 homolog 4|R51H3|RAD51 homolog D|RAD51-like protein 3|TRAD|RAD51D|RAD51L3

Background: Involved in the homologous recombination repair(HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA(ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

Poids moléculaire: 23-25 kDa

ID gène: 5892

UniProt: O75771