RRAGB anticorps
Aperçu rapide pour RRAGB anticorps (ABIN7118323)
Antigène
Voir toutes RRAGB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RRAGB antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- Ras-related GTP binding B
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- RRAGB (Ras-Related GTP Binding B (RRAGB))
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Autre désignation
- RRAGB
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Sujet
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Synonyms: Ras-related GTP-binding protein B (Rag B, RagB)|RRAGB
Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
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Poids moléculaire
- 40 kDa
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ID gène
- 10325
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UniProt
- Q5VZM2
Antigène
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