RNLS anticorps

N° du produit ABIN7118395

Cet anticorps Lapin Polyclonal détecte spécifiquement RNLS dans WB, IHC, IP et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RNLS anticorps (ABIN7118395)

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNLS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA

Détail du produit anti-RNLS anticorps

Fonction: RNLS antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: chromosome 10 open reading frame 59

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RNLS

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Autre désignation: RNLS

Sujet:

Synonyms: Renalase|Monoamine oxidase-C (MAO-C)|RNLS|C10orf59

Background: RNLS, also named as Renalase, C10orf59 and MAO-C, belongs to the renalase family. It is probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. RNLS degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. RNLS has physiologically relevant catecholamine-oxidizing activity.(PMID:15841207) This antibody is specific to RNLS.

Poids moléculaire: 35 kDa

ID gène: 55328

UniProt: Q5VYX0