RFC4 anticorps
Aperçu rapide pour RFC4 anticorps (ABIN7118400)
Antigène
Voir toutes RFC4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RFC4 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- replication factor C (activator 1) 4, 37kDa
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100, IP: 1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
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Autre désignation
- RFC4
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Sujet
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Synonyms: Replication factor C subunit 4|Activator 1 37 kDa subunit (A1 37 kDa subunit)|Activator 1 subunit 4|Replication factor C 37 kDa subunit (RF-C 37 kDa subunit, RFC37)|RFC4
Background: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
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Poids moléculaire
- 38 kDa
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ID gène
- 5984
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UniProt
- P35249
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Pathways
- Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA
Antigène
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