RPE65 anticorps

N° du produit ABIN7118420

L’anticorps anti-RPE65 Polyclonal Lapin est utilisé pour la détection de RPE65 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour RPE65 anticorps (ABIN7118420)

Antigène: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPE65 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RPE65 anticorps

Fonction: RPE65 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: retinal pigment epithelium-specific protein 65kDa

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RPE65

Antigène: RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))

Autre désignation: RPE65

Sujet:

Synonyms: Retinoid isomerohydrolase|All-trans-retinyl-palmitate hydrolase|Lutein isomerase|Meso-zeaxanthin isomerase|Retinal pigment epithelium-specific 65 kDa protein|Retinol isomerase|RPE65

Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A(all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH(isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Poids moléculaire: 65 kDa, 61 kDa

ID gène: 6121

UniProt: Q16518