RBM14 anticorps

N° du produit ABIN7118671

Cet anticorps Lapin Polyclonal détecte spécifiquement RBM14 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour RBM14 anticorps (ABIN7118671)

Antigène: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM14 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RBM14 anticorps

Fonction: RBM14 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: RNA binding motif protein 14

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RBM14

Antigène: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Autre désignation: RBM14

Sujet:

Synonyms: RNA-binding protein 14|Paraspeckle protein 2 (PSP2)|RNA-binding motif protein 14|RRM-containing coactivator activator/modulator|Synaptotagmin-interacting protein (SYT-interacting protein)|RBM14|SIP

Background: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1(PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex(which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ(PubMed:25385835).

Poids moléculaire: 70-75 kDa

ID gène: 10432

UniProt: Q96PK6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway