SUN1 anticorps
Aperçu rapide pour SUN1 anticorps (ABIN7118769)
Antigène
Voir toutes SUN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SUN1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- unc-84 homolog A(C. elegans)
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:5000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.1 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))
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Autre désignation
- SUN1
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Sujet
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Synonyms: SUN domain-containing protein 1|Protein unc-84 homolog A|Sad1/unc-84 protein-like 1|SUN1|KIAA0810|UNC84A
Background: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).
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Poids moléculaire
- 90 kDa
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ID gène
- 6821
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UniProt
- O94901
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Pathways
- Maintenance of Protein Location
Antigène
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