SRRM1 anticorps
Aperçu rapide pour SRRM1 anticorps (ABIN7118908)
Antigène
Voir toutes SRRM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SRRM1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- serine/arginine repetitive matrix 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))
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Autre désignation
- SRRM1
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Sujet
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Synonyms: Serine/arginine repetitive matrix protein 1|SR-related nuclear matrix protein of 160 kDa (SRm160)|Ser/Arg-related nuclear matrix protein|SRRM1|SRM160
Background: Part of pre-and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer(ESE)-dependent splicing activation by bridging together sequence-specific(SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP(SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double-or single-stranded nucleic acid substrates.
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Poids moléculaire
- 120-160 kDa
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ID gène
- 10250
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UniProt
- Q8IYB3
Antigène
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