SH3PXD2A anticorps (AA 385-533)

N° du produit ABIN7119018

Cet anticorps anti-SH3PXD2A est un anticorps Lapin Polyclonal détectant SH3PXD2A dans WB, ELISA, IHC et IF. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour SH3PXD2A anticorps (AA 385-533) (ABIN7119018)

Antigène: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3PXD2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SH3PXD2A anticorps

Épitope: AA 385-533

Fonction: SH3PXD2A antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 385-533aa

Immunogen: SH3 and PX domains 2A

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SH3PXD2A

Antigène: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Autre désignation: SH3PXD2A

Sujet:

Synonyms: SH3 and PX domain-containing protein 2A|Adapter protein TKS5|Five SH3 domain-containing protein|SH3 multiple domains protein 1|Tyrosine kinase substrate with five SH3 domains|SH3PXD2A|FISH|KIAA0418|SH3MD1|TKS5

Background: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.

Poids moléculaire: 140 kDa

ID gène: 9644

UniProt: Q5TCZ1