SNX17 anticorps

N° du produit ABIN7119355

Cet anticorps Lapin Polyclonal détecte spécifiquement SNX17 dans WB, ELISA, IHC, IP et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SNX17 anticorps (ABIN7119355)

Antigène: SNX17 (Sorting Nexin 17 (SNX17))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-SNX17 anticorps

Fonction: SNX17 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: sorting nexin 17

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SNX17

Antigène: SNX17 (Sorting Nexin 17 (SNX17))

Autre désignation: SNX17

Sujet:

Synonyms: Sorting nexin-17|SNX17|KIAA0064

Background: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate(PtdIns(3P)).

Poids moléculaire: 52 kDa

ID gène: 9784

UniProt: Q15036