SPATA13 anticorps

N° du produit ABIN7119403

Cet anticorps Lapin Polyclonal détecte spécifiquement SPATA13 dans WB, ELISA et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SPATA13 anticorps (ABIN7119403)

Antigène: SPATA13 (Spermatogenesis Associated 13 (SPATA13))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPATA13 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-SPATA13 anticorps

Fonction: SPATA13 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: spermatogenesis associated 13

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SPATA13

Antigène: SPATA13 (Spermatogenesis Associated 13 (SPATA13))

Autre désignation: SPATA13

Sujet:

Synonyms: Spermatogenesis-associated protein 13|APC-stimulated guanine nucleotide exchange factor 2 (Asef2)|SPATA13

Background: Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Poids moléculaire: 75 kDa

ID gène: 221178

UniProt: Q96N96