SF3B2 anticorps
Aperçu rapide pour SF3B2 anticorps (ABIN7119435)
Antigène
Voir toutes SF3B2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SF3B2 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- splicing factor 3b, subunit 2, 145kDa
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))
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Autre désignation
- SF3B2
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Sujet
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Synonyms: Splicing factor 3B subunit 2|Pre-mRNA-splicing factor SF3b 145 kDa subunit (SF3b145)|Spliceosome-associated protein 145 (SAP 145)|SF3B2|SAP145
Background: This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
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Poids moléculaire
- 140 kDa
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ID gène
- 10992
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UniProt
- Q13435
Antigène
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