SF3B2 anticorps (AA 775-825)

N° du produit ABIN7453783

Détail du produit anti-SF3B2 anticorps

Antigène: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Épitope: AA 775-825

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SF3B2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-SF3b145/SAP145 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 775 and 825

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SF3B2

Antigène: SF3B2 (Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Autre désignation: SF3b145/SAP145 (SF3B2 Produits)

Synonymes: anticorps 145kDa, anticorps 2610311M13Rik, anticorps 2810441F20Rik, anticorps B230398H18Rik, anticorps SAP145, anticorps SF3b1, anticorps SF3b145, anticorps SF3b150, anticorps SF3B2, anticorps cus1, anticorps sap145, anticorps sf3b145, anticorps sf3b150, anticorps Cus1, anticorps SF3B145, anticorps splicing factor 3b, subunit 2, anticorps splicing factor 3b subunit 2, anticorps splicing factor 3B subunit 2, anticorps splicing factor 3b subunit 2 L homeolog, anticorps Sf3b2, anticorps SF3B2, anticorps LOC714747, anticorps sf3b2.L, anticorps sf3b2

Sujet: Background: SF3b145/SAP145 is a 145 kDa subunit of the splicing factor 3B (SF3B) protein complex. The SF3B complex is composed of at least 8 subunits (SF3B1 through SF3B8). SF3A along with SF3B and a 12S RNA unit are components of the 17S U2 small nuclear ribonucleoprotein complex (U2 snRNP) involved in pre-mRNA splicing. In this complex SF3B2 interacts directly with SF3B4 and associates with the pre-mRNA upstream of the branch site at the anchoring site. SF3A and SF3B may play a role in anchoring the U2 snRNP to the pre-mRNA upstream of the intron's branch site.

ID gène: 10992

UniProt: Q13435