SOX2 anticorps (AA 129-317)

N° du produit ABIN7119471

Cet anticorps anti-SOX2 est un anticorps Lapin Polyclonal détectant SOX2 dans WB, ELISA, IHC et IF. Adapté pour Humain, Souris, Rat et Poisson zèbre (Danio rerio).

Aperçu rapide pour SOX2 anticorps (AA 129-317) (ABIN7119471)

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SOX2 anticorps

Épitope: AA 129-317

Fonction: SOX2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 129-317aa

Immunogen: SRY(sex determining region Y)-box 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:2000-1:20000, IHC: 1:50-1:200, IF: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SOX2

Antigène: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Autre désignation: SOX2

Sujet:

Synonyms: Transcription factor SOX-2|SOX2

Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity).

Poids moléculaire: 34 kDa

ID gène: 6657

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis