DR1 anticorps

N° du produit ABIN7119791

L’anticorps Lapin Polyclonal anti-DR1 a été validé pour WB, IHC, ELISA et IF. Il convient pour détecter DR1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DR1 anticorps (ABIN7119791)

Antigène: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-DR1 anticorps

Fonction: DR1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: down-regulator of transcription 1, TBP-binding (negative cofactor 2)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur DR1

Antigène: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Autre désignation: DR1

Sujet:

Synonyms: Protein Dr1|Down-regulator of transcription 1|Negative cofactor 2-beta (NC2-beta)|TATA-binding protein-associated phosphoprotein|DR1

Background: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Poids moléculaire: 19 kDa

ID gène: 1810

UniProt: Q01658