TEX14 anticorps

N° du produit ABIN7119846

Cet anticorps anti-TEX14 est un anticorps Lapin Polyclonal détectant TEX14 dans WB, ELISA, IHC et IP. Adapté pour Humain et Souris.

Aperçu rapide pour TEX14 anticorps (ABIN7119846)

Antigène: TEX14 (Testis Expressed 14 (TEX14))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEX14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-TEX14 anticorps

Fonction: TEX14 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: testis expressed 14

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TEX14

Antigène: TEX14 (Testis Expressed 14 (TEX14))

Autre désignation: TEX14

Sujet:

Synonyms: Inactive serine/threonine-protein kinase TEX14|Protein kinase-like protein SgK307|Sugen kinase 307|Testis-expressed sequence 14|Testis-expressed sequence 14 protein|TEX14|SGK307

Background: Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).

Poids moléculaire: 180-200 kDa, 106 kDa

ID gène: 56155

UniProt: Q8IWB6

Pathways: Maintenance of Protein Location