TXNRD1 anticorps

N° du produit ABIN7119913

Cet anticorps Lapin Polyclonal détecte spécifiquement TXNRD1 dans WB, IHC, ELISA, IP, IF et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TXNRD1 anticorps (ABIN7119913)

Antigène: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TXNRD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-TXNRD1 anticorps

Fonction: TXNRD1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: thioredoxin reductase 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TXNRD1

Antigène: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Autre désignation: TXNRD1

Sujet:

Synonyms: Thioredoxin reductase 1, cytoplasmic (TR)|Gene associated with retinoic and interferon-induced mortality 12 protein (GRIM-12, Gene associated with retinoic and IFN-induced mortality 12 protein)|KM-102-derived reductase-like factor|Peroxidase TXNRD1|Thioredoxin reductase TR1|TXNRD1|GRIM12|KDRF

Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Poids moléculaire: 54 kDa

ID gène: 7296

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis