TRIP10 anticorps

N° du produit ABIN7119955

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIP10 dans WB, ELISA et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TRIP10 anticorps (ABIN7119955)

Antigène: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIP10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-TRIP10 anticorps

Fonction: TRIP10 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: thyroid hormone receptor interactor 10

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:500-1:5000, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TRIP10

Antigène: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Autre désignation: TRIP10

Sujet:

Synonyms: Cdc42-interacting protein 4|Protein Felic|Salt tolerant protein (hSTP)|Thyroid receptor-interacting protein 10 (TR-interacting protein 10, TRIP-10)|TRIP10|CIP4|STOT|STP

Background: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling(By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Poids moléculaire: 75-85 kDa

ID gène: 9322

UniProt: Q15642