TRIP4 anticorps
Aperçu rapide pour TRIP4 anticorps (ABIN7119957)
Antigène
Voir toutes TRIP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- TRIP4 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- thyroid hormone receptor interactor 4
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:5000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))
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Autre désignation
- TRIP4
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Sujet
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Synonyms: Activating signal cointegrator 1 (ASC-1)|Thyroid receptor-interacting protein 4 (TR-interacting protein 4, TRIP-4)|TRIP4|RQT4
Background: Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation(PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation(By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B(PubMed:12077347). May play a role in the development of neuromuscular junction(PubMed:26924529).
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Poids moléculaire
- 66 kDa
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ID gène
- 9325
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UniProt
- Q15650
Antigène
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