TRIAP1 anticorps

N° du produit ABIN7120027

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIAP1 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TRIAP1 anticorps (ABIN7120027)

Antigène: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIAP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TRIAP1 anticorps

Fonction: TRIAP1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: TP53 regulated inhibitor of apoptosis 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TRIAP1

Antigène: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Autre désignation: TRIAP1

Sujet:

Synonyms: TP53-regulated inhibitor of apoptosis 1|Protein 15E1.1|WF-1|p53-inducible cell-survival factor (p53CSV)|TRIAP1|15E1.1

Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).

Poids moléculaire: 32 kDa

ID gène: 51499

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling