TDP2 anticorps

N° du produit ABIN7120444

Cet anticorps Lapin Polyclonal détecte spécifiquement TDP2 dans WB, ELISA et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TDP2 anticorps (ABIN7120444)

Antigène: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-TDP2 anticorps

Fonction: TDP2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: TRAF and TNF receptor associated protein

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TDP2

Antigène: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Autre désignation: TDP2

Sujet:

Synonyms: Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2, hTDP2)|5'-tyrosyl-DNA phosphodiesterase (5'-Tyr-DNA phosphodiesterase)|ETS1-associated protein 2|ETS1-associated protein II (EAPII)|TRAF and TNF receptor-associated protein|Tyrosyl-RNA phosphodiesterase|VPg unlinkase|TDP2|EAP2|TTRAP

Background: TTRAP is a 5-prime tyrosyl-DNA phosphodiesterase that is required for efficient repair of topoisomerase II-induced DNA double-strand breaks. Thus it can remove lots of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, generating a free 5' phosphate to DNA. It also has 3'-tyrosyl DNA phophodiesterase activity, but not so efficient as TDP1. TTRAP functions as a negative regulator of ETS1 and inhibit nuclear factor-kappa-B activation.

Poids moléculaire: 44 kDa

UniProt: O95551