USP5 anticorps

N° du produit ABIN7120529

L’anticorps Souris Monoclonal anti-USP5 a été validé pour WB et ELISA. Il convient pour détecter USP5 dans des échantillons de Humain.

Aperçu rapide pour USP5 anticorps (ABIN7120529)

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp USP5 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 6G1

Détail du produit anti-USP5 anticorps

Fonction: USP5 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin specific peptidase 5(isopeptidase T)

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur USP5

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Autre désignation: USP5

Sujet:

Synonyms: Ubiquitin carboxyl-terminal hydrolase 5|Deubiquitinating enzyme 5|Isopeptidase T|Ubiquitin thioesterase 5|Ubiquitin-specific-processing protease 5|USP5|ISOT

Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Poids moléculaire: 93 kDa

ID gène: 8078

UniProt: P45974